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Remit

 

Our remit is to research diseases of the liver, pancreas and biliary tree and to educate healthcare professionals and those affected about outcomes. In addition, we seek to pass on the benefit of new-found knowledge directly to patients as quickly as possible, and so have supported a number of additional initiatives to support this.

 
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Research makes a difference


Of all the causes to which people in the UK donate their money, research is the most popular. The importance of charitable donations to scientific and medical research in this country is hugely significant.

Today, over a third of all medical research in the UK is funded by charities.  And its impact can be measured, with incredible results.

In the 1970s, fewer than a quarter of people with cancer survived. Due to significant advances in diagnosis and treatment, survival rates have doubled over the last forty years – today, half of people diagnosed with cancer will survive.

In 1996, the total life expectancy for 20 year-old infected with HIV was 39 years. By 2011, that life expectancy had reached 70 years. Today, it almost matches the life expectancy of someone without HIV.

Disease of the liver, pancreas and biliary tree are often described as ‘silent’ – they develop quietly and only become apparent when they’re advanced and the options for treatment are limited. At LAP Research, we’re focused on identifying markers that can spot these illnesses much earlier, and on novel, specific treatments. Ultimately, this can make a real difference.

LAP Research is currently undertaking some very exciting projects. Please click on the headings below and find out how they are coming on...

 

Awards


In addition to research projects, we are keen to provide direct benefit of the very latest knowledge, clinical skill and cutting-edge technology to people affected by these diseases as quickly as possible. To this end, LAP Research has donated an ICG Clearance Machine to Barts Hospital which assesses liver function to help determine the right course of treatment. The charity is also able to fund an award which enables clinical skills and learnings from other parts of the world to be brought to surgeons in hospitals in the UK.

 
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The Eileen Albert & LAP Research Travelling Fellowship 2016


The 2016 prize-winner was Mr Sas Banerjee who travelled to the National Cancer Centre Hospital (NCCH) in Tokyo to learn new techniques that have the ability of reducing the risk of HPB disease in terms of metastases.

Mr Banerjee is a Consultant General & Colorectal Surgeon in London and works at Queens Hospital (Barking Havering Redbridge NHS University Trust). He is a specialist bowel cancer surgeon and manages patients who have been identified with secondary liver cancer collaboratively with his Hepatobiliary surgical colleagues. Identifying and treating early bowel cancer in the minimally invasive way improves the outcomes for the patients and reduces the risk of distant spread of the cancer including to the liver and this was the purpose of the trip to Tokyo.

 
 

Colonic polyps can transform into bowel cancer and that can then spread to the liver. The skills for early therapeutic removal of polyps at most centres in the UK are restricted to polypectomy with endoscopic mucosal resection (EMR). More complex polyps that are not amenable to be removed endoscopically may need a complex operation to remove a segment of the colon. The NCCH has a world class practice that allows complex polyps (even with early cancer or near cancer) to be treated with endoscopic techniques like Endosubmucosal Dissection (ESD) and this was the predominant focus of the visit.

In Tokyo for 4 weeks as a Visiting Fellow he was mentored by a world-renowned team led by Dr Yutaka Saito. During the Fellowship he was able to see multiple patients who had treatment with ESD.

Since his return to the UK, Mr Banerjee has attended the Hands on ESD Course (June 2016) & the Endo-Live conference (November 2016) at King's College Hospital, He has joined the UK ESD Interest Group led by Dr Sunil Dolwani (Cardiff) with 2 of his other colleagues from his NHS Trust. One of his colleagues also has travelled to the NCCH and a working group has been brought together to provde the technique at the Trust. Dr Saito and his colleagues have offered to visit the Trust and help with mentoring and setting up of courses and the practice.

After returning from Tokyo, Mr Banerjee participated in a 10K run in April 2016 to raise funds for LAP Research.

The Eileen Albert & LAP Research Travelling Fellowship 2014


The prize-winner for this award was Mr Ajay Belgaumkar who received funds to enable him to travel to Paris to further his surgical education into HPB disease.

“This was a unique opportunity to learn the techniques for major laparoscopic HPB resection from an acknowledged master"

“I undertook the IHPBA-accredited fellowship in advanced laparoscopic liver and pancreas surgery with Professor Brice Gayet, at L'Institut Mutualiste Montsouris. The IMM experience of laparoscopic HPB surgery is one of the largest in the world and includes >600 laparoscopic liver resections and >250 major pancreatic resections, as well as a large caseload of other digestive surgery. The Unit has a long track record of training fellows from the USA and Japan.

This was a unique opportunity to learn the techniques for major laparoscopic HPB resection from an acknowledged master, including an unparalleled opportunity to understand the tricks and pitfalls. My responsibilities include participation in theatre for HPB and digestive surgery cases on between 3-5 lists per week, attendance at Staff and Oncology MDT meetings and preparation of research papers and edited videos from the departmental clinical database. In particular, the techniques I have learnt include laparoscopic anatomical segmental liver resection (with use of transthoracic trocars), laparoscopic hilar dissection for major hepatectomy, laparoscopic liver ultrasound guided resection, and posterior 'artery-first' approach to laparoscopic Whipple's. I also had access to the Robotic theatres with the Urologists, where I was able to learn about the theatre set up and instrumentation of the Da Vinci robotic system. During my time in Paris, I also visited Prof Daniel Azoulay's team at Hopital Henri Mondor, who have a burgeoning experience in Robotic minimally invasive liver resection and robotic whipple's."